Supporting genetic studies for diabetes and other diseases

The Human Biological Data Interchange (HBDI) is the genetics division of NDRI. Created in 1988, HBDI has medical history and genealogical data on over 6700 families who are affected by type 1 diabetes. In addition, HBDI maintains a repository of DNA and immortalized cell lines collected from 500 families. This database and repository was originally created to help researchers uncover the genetic causes of type 1 diabetes. Today, it is also used by researchers who study type 2 diabetes, diabetic complications, autoimmune diseases, kidney disease, and other disorders.

HBDI Resources and Services

The following resources and services are available to researchers through HBDI:

International Type 1 Diabetes Database
This database includes more than 6700 families with diabetes, related complications and other genetic diseases. There are extensive genealogical and medical histories for more than 90,000 individuals. NDRI conducts searches of the database for approved research requests.

HBDI Catalog
The catalog contains 503 family pedigrees with associated cell lines, DNA, and serum for research. Also available are HLA-typing and auto-antibody test results for diabetes families in the catalog.

HBDI Repository
The HBDI repository contains cell lines, DNA, and HLA typing information from 480 families, and frozen buffy coats from 23 families, all with Type 1 diabetes. We have recently expanded our repository to include specimens from individuals with rare diseases.

Customized Collections
NDRI will collect data from patients and physicians, conduct phone interviews and collect blood and other specimens for research on request.

For an HBDI catalog, click here.

For a researcher application, click here.

To contact us, click here.