National Disease Research Interchange

National Institutes of Health funds Human Tissues and Organs for Research Resource Program

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National Disease Research Interchange

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National Disease Research Interchange

Researchers Respond: How COVID-19 Has Impacted Research With Human Tissue

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National Disease Research Interchange

Making strides to treat common and rare diseases with diverse programs & intiatives

National Disease Research Interchange

Supporting breakthrough scientific discoveries in Alzheimer’s Disease & AD Related Dementia (AD/ADRD)

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National Disease Research Interchange

Giving patients and families an opportunity to leave a meaningful legacy

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Serving Researchers Worldwide

Every year, NDRI distributes biospecimens to hundreds of investigators around the world who are working to advance many areas of science and healthcare. NDRI makes it easy for approved investigators to get much-needed biospecimens prepared, preserved and shipped precisely according the specific needs of the research protocol.

Request Process Request Tissue
1. Customized
Biospecimen acquisition and processing tailored to specific protocol requirements
2. Timely
Responsive 24/7/365 call center for requests and biospecimen distribution
3. Diverse
40 years of experience distributing nearly every human tissue and organ
4. Ethical
Informed consent and regulation compliant material handling
Serving Researchers Worldwide

Every year, NDRI distributes biospecimens to hundreds of investigators around the world who are working to advance many areas of science and healthcare. NDRI makes it easy for approved investigators to get much-needed biospecimens prepared, preserved and shipped precisely according the specific needs of the research protocol.

Request Process Request Tissue
1. Customized
Biospecimen acquisition and processing tailored to specific protocol requirements
2. Timely
Responsive 24/7/365 call center for requests and biospecimen distribution
3. Diverse
40 years of experience distributing nearly every human tissue and organ
4. Ethical
Informed consent and regulation compliant material handling
Donor Stories | Sarah Gray
“My son’s life was relevant not just to my family, but to the larger community. Thomas is changing medical history.”
Donor Stories | Cray Family
“The decision to donate our son Ian’s organs and tissue was the only bright spot in the darkest day of our lives."
Donor Stories | Laurie Gelb
“…consider offering down the road something worth more than money to NDRI."
Neurological Programs
A resource for scientists studying autism and traumatic brain injury
LungMAP Initiative
Supporting research into the causes of childhood lung disease
Joslin Medalist
Providing tissues to help investigators prevent, treat and cure Type 1 diabetes
Partnerships & Programs for Progress

Researchers continue to recognize NDRI as an invaluable partner as the need for human biomaterials grow. In response, NDRI has developed specialized programs to increase the supply of human tissues and organs for specific areas of research and has established a network of human tissue collection sites throughout the country to procure them.

Become a Partner See Our Programs
News & Events 
Dec 01, 2021

-Philadelphia-based National Disease Research Interchange (NDRI) announces the election of Paul M. Lieberman, Ph.D., to its Board. Lieberman is the Hilary Koprowski, M.D., Endowed Professor, leader of the Gene Expression and Regulation Program, and director of the Center for Chemical Biology & Translational Medicine at The Wistar Institute, a biomedical research leader in cancer, immunology, infectious disease, and vaccine development. Elected on November 12 to a three-year term, Lieberman will bring his experience and insight to the nation’s leading source of human organs, cells and tissues for research.

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Nov 03, 2021

 The National Disease Research Interchange (NDRI) is pleased to announce its recovery network partners for the developmental Genotype-Tissue Expression (dGTEx) project. The dGTEx project is the first comprehensive public resource correlating gene expression and genetic variation in pediatric tissues from all major organ systems in the human body.  NDRI will partner with multiple organ procurement organizations/tissue banks across the United States.

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Sep 30, 2021

NDRI and collaborators were awarded a research grant of $12.5M over 5 years to collaborate on the developmental Genotype Expression (dGTEx) project

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Jul 27, 2021

NDRI was recently awarded a research resource grant of $334,446 from the National Institute on Aging (NIA) to support the development of the Ocular Tissue Resource for Alzheimer’s Disease (OTRAD). While significant advances continue to be made with the identification of blood-based biomarkers for Alzheimer’s disease (AD), there is an emergent interest in the use of ocular imaging or other ocular biomarkers as a parallel approach in early detection of the disease.

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Jun 28, 2021

NDRI issued a public comment on the Centers for Medicare and Medicaid Services proposed rule entitled "Medicare Program: Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the Long Term Care Hospital Prospective Payment System and Proposed Policy Changes and Fiscal Year 2022 Rates; Quality Programs and Medicare Promoting Interoperability Program Requirements for Eligible Hospitals and Critical Access Hospitals; Proposed Changes to Medicaid Provider Enrollment". This rule dramatically discourages the use and acquisition of human tissues for biomedical research- our comment was posted on June 22. You can read the full submission on our website here: https://ndriresource.org/uploads/attachments/ckqgogkpsedvv96u16sf1qfss-ndripubliccomment.pdf

Learn More
Dec 01, 2021

-Philadelphia-based National Disease Research Interchange (NDRI) announces the election of Paul M. Lieberman, Ph.D., to its Board. Lieberman is the Hilary Koprowski, M.D., Endowed Professor, leader of the Gene Expression and Regulation Program, and director of the Center for Chemical Biology & Translational Medicine at The Wistar Institute, a biomedical research leader in cancer, immunology, infectious disease, and vaccine development. Elected on November 12 to a three-year term, Lieberman will bring his experience and insight to the nation’s leading source of human organs, cells and tissues for research.

Learn More
Nov 03, 2021

 The National Disease Research Interchange (NDRI) is pleased to announce its recovery network partners for the developmental Genotype-Tissue Expression (dGTEx) project. The dGTEx project is the first comprehensive public resource correlating gene expression and genetic variation in pediatric tissues from all major organ systems in the human body.  NDRI will partner with multiple organ procurement organizations/tissue banks across the United States.

Learn More
Sep 30, 2021

NDRI and collaborators were awarded a research grant of $12.5M over 5 years to collaborate on the developmental Genotype Expression (dGTEx) project

Learn More
Jul 27, 2021

NDRI was recently awarded a research resource grant of $334,446 from the National Institute on Aging (NIA) to support the development of the Ocular Tissue Resource for Alzheimer’s Disease (OTRAD). While significant advances continue to be made with the identification of blood-based biomarkers for Alzheimer’s disease (AD), there is an emergent interest in the use of ocular imaging or other ocular biomarkers as a parallel approach in early detection of the disease.

Learn More
Jun 28, 2021

NDRI issued a public comment on the Centers for Medicare and Medicaid Services proposed rule entitled "Medicare Program: Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the Long Term Care Hospital Prospective Payment System and Proposed Policy Changes and Fiscal Year 2022 Rates; Quality Programs and Medicare Promoting Interoperability Program Requirements for Eligible Hospitals and Critical Access Hospitals; Proposed Changes to Medicaid Provider Enrollment". This rule dramatically discourages the use and acquisition of human tissues for biomedical research- our comment was posted on June 22. You can read the full submission on our website here: https://ndriresource.org/uploads/attachments/ckqgogkpsedvv96u16sf1qfss-ndripubliccomment.pdf

Learn More

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NDRI is a Not-For-Profit (501c3) Corporation.