The use of human biospecimens plays a key role in accelerating scientific discoveries in neurological research by providing scientists with a direct experimental model system to advance understanding of pathogenesis and treatment of neurological disease, including Alzheimer’s disease and related dementias (AD/ADRD). Access to the appropriate human biospecimen can be challenging for some investigators. To address thus gap, NDRI’s Human Tissue and Organs for Research Resource (HTORR) Program was recently awarded an administrative supplemental grant from the National Institute on Aging (NIA) to support Alzheimer’s Disease and AD-related dementia (AD/ADRD) studies that require whole brain and other tissues for their experimental analysis.
The ADBR program can tailor acquisition of both whole brain and other tissue samples to meet the specific needs of each research project. The ADBR can provide tissue types for a wide range of experimental needs. This includes:
- Fixed tissue, frozen tissue, or fresh tissue shipped on ice in culture media with antibiotics
- CNS and PNS structures – whole brain, brain tissue samples, spinal cord, dorsal root ganglia,
peripheral nerves
- Tissues from any body system
- Samples from both AD/ADRD and non-diseased, control donors are available
