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You are currently filtering by: 2016 Hepatology liver

Hepatology • 2016 • The Journal of Biological Chemistry 291(2): 894-903. PMID: 26601943.
RNA Editing Modulates Human Hepatic Aryl Hydrocarbon Receptor Expression by Creating MicroRNA Recognition Sequence.

Nakano M, Fukami T, Gotoh S, Takamiya M, Aoki Y, Nakajima M

Full Article
Hepatology • 2016 • Drug Metabolism and Disposition 44(9): 1524-1535. PMID: 27342868.
Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters.

Chow EC, Wang JZ, Quach HP, Tang H, Evans DC, Li AP, Silva J, Pang KS

Full Article
Hepatology • 2016 • Biochemical Pharmacology 116:153-161.
Human arylacetamide deacetylase hydrolyzes ketoconazole to trigger hepatocellular toxicity.

Fukami T, Iida A, Konishi K, Nakajima

Full Article
Hepatology • 2016 • Biochemical Pharmacology 117: 78-87. PMID: 27531059.
Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver.

Papageorgiou I, Freytsis M, Court MH

Full Article
Hepatology • 2016 • Xenobiotica 46(5): 406-415. PMID: 26366946.
Soy isoflavone metabolism in cats compared with other species: urinary metabolite concentrations and glucuronidation by liver microsomes.

Redmon JM, Shrestha B, Cerundolo R, Court MH

Full Article
Hepatology • 2016 • Toxicological Sciences 154(2): 368-380. PMID: 27613715.
Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells.

Ren Z, Chen S, Zhang J, Doshi U, Li AP, Guo L

Full Article
Hepatology • 2016 • Xenobiotica 47(1): 1-10. PMID: 26999266.
Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms.

Street CM, Zhu Z, Finel M, Court MH

Full Article
• 2016 • Drug Metabolism, Disposition dmd.116.071902. PMID: 27758804.
Tramadol metabolism to O-desmethyl tramadol (M1), N-desmethyl tramadol (M2) by dog liver microsomes: Species comparison, identification of responsible canine cytochrome P-450s (CYPs).

Perez Jimenez TE, Mealey KL, Grubb TL, Greene SA, Court MH

Full Article
• 2016 • PLoS One 11(7): e0158419. PMID: 27404108.
Hepatitis C Virus Frameshift/Alternate Reading Frame Protein Suppresses Interferon Responses Mediated by Pattern Recognition Receptor Retinoic-Acid-Inducible Gene-I.

Park SB, Seronello S, Mayer W, Ojcius DM

Full Article

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