NDRI: Publications

• 2018 • Diabetes. 2018 Sep;67(9):1807-1815

The Dysregulation of the DLK1-MEG3 Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs

Kameswaran V, Golson ML, Ramos-Rodríguez M, Ou K, Wang YJ, Zhang J, Pasquali L, Kaestner KH

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• 2017 • Journal of Clinical Research in Pediatric Endocrinology 9(3):260-264. PMID: 28663158.

An ABCC8 Nonsense Mutation Causing Neonatal Diabetes Through Altered Transcript Expression.

Flanagan SE1, Dũng VC, Houghton JAL, De Franco E, Ngoc CTB, Damhuis A, Ashcroft FM, Harries LW, Ellard S

Full Article

• 2017 • Scientific Reports 7:45319. PMID: 28378743.

Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes.

Dharmadhikari G, Stolz K, Hauke M, Morgan NG, Varki A, de Koning E, Kelm S, Maedler K

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• 2017 • Proceedings of the National Academy of Sciences of the United States of America 114(9):2301-2306. PMID: 28193859.

Genetic regulatory signatures underlying islet gene expression and type 2 diabetes.

Varshney A, Scott LJ, Welch RP, Erdos MR, Chines PS, Narisu N, Albanus RD, Orchard P, Wolford BN, Kursawe R, Vadlamudi S, Cannon ME, Didion JP, Hensley J, Kirilusha A; NISC Comparative Sequencing Program, Bonnycastle LL, Taylor DL, Watanabe R, Mohlke KL, Boehnke M, Collins FS, Parker SC, Stitzel ML

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• 2017 • Current Opinion in Endocrinology, Diabetes and Obesity 24(2):98-102. PMID: 28099204.

Narrowing in on the anti-β cell-specific T cells: looking 'where the action is'.

Kent SC, Babon JA

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• 2016 • PLoS One 11(3): e0151329. PMID: 27008626.

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic-Cell.

Deeney JT, Belkina AC, Shirihai OS, Corkey BE, Denis GV

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