NDRI: Publications

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• 2019 • Proquest Dissertations Publishing

Human cytochromes mediating in vitro metabolism of lurasidone

Zixuan Wei

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• 2019 • Drug Metabolism and Pharmacokinetics

Characterization of human UGT2A3 expression using a prepared specific antibody against UGT2A3

Gotoh-Saito S, Abe T, Furukawa Y, Oda S, Yokoi T, Finel M, Hatakeyama M, Fukami T, Nakajima M

Full Article

• 2019 • The Journal of Infectious Diseases

Single Hepatocyte Hepatitis B Virus Transcriptional Landscape in HIV Coinfection

Ashwin Balagopal, Hyon S Hwang, Tanner Grudda, Jeffrey Quinn, Richard K Sterling, Mark S Sulkowski, Chloe L Thio

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• 2019 • Biochemical Pharmacology

Methylation of adenosine at the N6 position post-transcriptionally regulates hepatic P450s expression

Masataka Nakano, Kyoko Ondo, Seiya Takemoto, Tatsuki Fukami, Miki Nakajima

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• 2019 • Chirality

Investigation of the chiral recognition ability of human carboxylesterase 1 using indomethacin esters

Masato Takahashi, Daisuke Takani, Masami Haba, Masakiyo Hosokawa

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• 2018 • Biopharmaceutics Drug Disposition

Alterations in gene expression in vitamin D-deficiency: Down-regulation of liver Cyp7a1 and renal Oat3 in mice.

Quach HP, Noh K, Hoi SY, Bruinsma A, Groothuis GMM, Li AP, Chow ECY, Pang KS

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• 2018 • Molecular Therapy

Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor Expression.

Willoughby JLS, Chan A, Sehgal A, Butler JS, Nair JK, Racie T, Shulga-Morskaya S, Nguyen T, Qian K, Yucius K, Charisse K, van Berkel TJC, Manoharan M, Rajeev KG, Maier MA, Jadhav V, Zimmermann TS

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• 2018 • J Clin Invest 2018 Oct 1;128(10): 4501-4509

No recovery of replication-competent HIV-1 from human liver macrophages

Kandathil AJ, Sugawara S, Goyal A, Durand CM, Quinn J, Sachithanandham J, Cameron AM, Bailey JR, Perelson AS, Balagopal A.

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• 2018 • Biopharm Drug Dispos. 2018 Mar;39(3)

Inhibitory effects of sulfonylureas and non-steroidal anti-inflammatory drugs on in vitro metabolism of canagliflozin in human liver microsomes

Algeelani S, Alkhelb D, Greenblatt DJ

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• 2018 • Xenobiotica. 2018 Aug;48(8):764-769

In vitro inhibition of human UGT isoforms by ritonavir and cobicistat

Algeelani S, Alam N, Hossain MA, Mikus G, Greenblatt DJ

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