Partners

NDRI’s work is made possible through strong partnerships with federal biomedical research agencies and the generous support of philanthropic organizations dedicated to patient advocacy.

Some of our funding partners, including the National Institutes of Health, have supported us for decades in recognition of the critical role that human tissues and organs play in advancing biomedical research.

 

Human Tissues and Organs for Research Resource (HTORR) Parent Grant

Established in 1987, NDRI’s Human Tissues and Organs for Research Resource (HTORR) Program has been funded by The National Institutes of Health (NIH) to support research programs across multiple disciplines. The HTORR program provides NIH-funded Principal Investigators with donated normal and diseased human biospecimens to support the advancement of their research. Below is a list of NIH institutes that support the HTORR program.

Office of the Director
National Institute of Allergy and Infectious Diseases (NIAID)
National Heart, Lung and Blood Institute (NHLBI)
National Eye Institute (NEI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAIMS)

For more information on NDRI’s HTORR Program visit:
NDRI HTORR Resource Page
NIH HTORR Resource
NIAID HTORR Resource


HTORR Supplements

To expand the impact of HTORR beyond the scope of the parent award, the HTORR program has included several administrative supplement awards to support to high priority and emerging research, and training initiatives for the NIH. The list of awards and supporting NIH institutions includes:

  • HIV Program – National Institute of Allergy and Infectious Diseases (NIAID)
  • Alzheimer’s Disease Biospecimen Resource (ADBR) Program – National Institute on Aging (NIA)
  • Ocular Procurement for Alzheimer’s Disease (OTRAD) Program – National Institute on Aging (NIA)
  • Autism Spectrum Disorder (ASD) Brain Recovery Program – National Institute of Mental Health (NIMH)
  • Alterations & Renovations (A&R) Program – Office of Research Infrastructure Program (ORIP)
  • Diversity Supplement Program – Office of Research Infrastructure Program (ORIP)

For more information visit the NDRI HTORR page.

Developmental Genotype-Tissue Expression (dGTEx) Project

The Developmental Genotype-Tissue Expression (dGTEx) project is an NIH-supported initiative to establish a scientific research resource of gene expression patterns in multiple healthy reference neonatal, pediatric, and adolescent tissues. NDRI serves as the lead for the Biospecimen Procurement Center (BPC), in collaboration with Children’s Hospital of Philadelphia, the University of Maryland School of Medicine, Johns Hopkins All Children’s Hospital, and six partner OPOs. The BPC is responsible for providing a multi-institutional effort with extensive expertise in pediatric recoveries, research, pathology, imaging, and biobanking.

dGTEx Funding Partners:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)

For more information on dGTEx visit:
dGTEx.org
dGTEx Family Resource Page

Somatic Mosaicism Across Human Tissues (SMaHT) Network

Somatic Mosaicism Across Human Tissues (SMaHT) Network is an NIH Common Fund program that will provide the first comprehensive public resource for analyzing genetic variation due to somatic mosaicism in human tissues from all developmental layers in the human body. NDRI serves as the lead for the Tissue Procurement Center (TPC), in collaboration with the University of Maryland School of Medicine, Johns Hopkins All Children’s Hospital, and three partner OPOs. The TPC is responsible for collecting, storing, and distributing multiple tissues across body systems from a diverse pool of organ and tissue donors for the SMaHT network.

SMaHT Funding Partner:
Office of the Director (OD), Office of Strategic Coordination

For more information on SMaHT visit:
SMaHT.org
NIH SMaHT Resource

NDRI also partners with many corporate and non-profit partners. Some of our not-for-profit partners are below:

ALS Boston VA Brain Bank

To advance research on amyotrophic lateral sclerosis (ALS), often called Lou Gehrig’s disease, the Department of Veterans Affairs Biorepository Brain Bank (VABBB) collects, processes, stores and distributes ALS biospecimens for future scientific studies. NDRI helps VABBB obtain the samples they need to build the biorepository, or human tissue bank.

Bay Area Lyme Foundation

Lyme disease is a tick-borne infection caused by Borrelia burgdorferi bacteria. The Centers for Disease Control and Prevention (CDC) estimates that each year as many as 300,000 people in the United States are diagnosed with Lyme disease. NDRI is partnering with the Bay Area Lyme Foundation and its Lyme Disease Biobank to build a system for collecting and banking a diverse group of biospecimens for use by the Lyme disease research community.

Cystic Fibrosis Foundation

The Cystic Fibrosis (CF) Foundation is committed to finding a cure for CF. Since 2004, the CF Foundation has funded NDRI to provide a reliable source of human tissues from CF donors with different genotypes to facilitate research and drug development. NDRI has continuously met those needs by providing countless high-quality biospecimens, which the foundation can use in studies to further promote individualized treatment and specialized care for individuals affected by the disease.

National ALS Registry – Agency for Toxic Substances and Disease Registry (ATSDR)

NDRI has a special focus on Amyotrophic lateral sclerosis (ALS) through collaborations with the National ALS Biorepository. McKing Consulting Corporation contracted NDRI to participate in a study to explore methods for collecting and banking brain tissues from patients enrolled in the National ALS Registry, which is maintained by the federal Agency for Toxic Substances and Disease Registry (ATSDR). NDRI is supporting the ongoing maintenance of ATSDR database of ALS patients and is leading the collection of biospecimens from those donors to develop the biorepository to support ALS research.

NDRI’s work is made possible through strong partnerships with federal biomedical research agencies and the generous support of philanthropic organizations dedicated to patient advocacy.

Some of our funding partners, including the National Institutes of Health, have supported us for decades in recognition of the critical role that human tissues and organs play in advancing biomedical research.

Human Tissues and Organs for Research Resource (HTORR) Parent Grant

Established in 1987, NDRI’s Human Tissues and Organs for Research Resource (HTORR) Program has been funded by The National Institutes of Health (NIH) to support research programs across multiple disciplines. The HTORR program provides NIH-funded Principal Investigators with donated normal and diseased human biospecimens to support the advancement of their research. Below is a list of NIH institutes that support the HTORR program.

Office of the Director
National Institute of Allergy and Infectious Diseases (NIAID)
National Heart, Lung and Blood Institute (NHLBI)
National Eye Institute (NEI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAIMS)

For more information on NDRI’s HTORR Program visit:
NDRI HTORR Resource Page
NIH HTORR Resource
NIAID HTORR Resource


HTORR Supplements

To expand the impact of HTORR beyond the scope of the parent award, the HTORR program has included several administrative supplement awards to support to high priority and emerging research, and training initiatives for the NIH. The list of awards and supporting NIH institutions includes:

  • HIV Program – National Institute of Allergy and Infectious Diseases (NIAID)
  • Alzheimer’s Disease Biospecimen Resource (ADBR) Program – National Institute on Aging (NIA)
  • Ocular Procurement for Alzheimer’s Disease (OTRAD) Program – National Institute on Aging (NIA)
  • Autism Spectrum Disorder (ASD) Brain Recovery Program – National Institute of Mental Health (NIMH)
  • Alterations & Renovations (A&R) Program – Office of Research Infrastructure Program (ORIP)
  • Diversity Supplement Program – Office of Research Infrastructure Program (ORIP)

For more information visit the NDRI HTORR page.

Developmental Genotype-Tissue Expression (dGTEx) Project

The Developmental Genotype-Tissue Expression (dGTEx) project is an NIH-supported initiative to establish a scientific research resource of gene expression patterns in multiple healthy reference neonatal, pediatric, and adolescent tissues. NDRI serves as the lead for the Biospecimen Procurement Center (BPC), in collaboration with Children’s Hospital of Philadelphia, the University of Maryland School of Medicine, Johns Hopkins All Children’s Hospital, and six partner OPOs. The BPC is responsible for providing a multi-institutional effort with extensive expertise in pediatric recoveries, research, pathology, imaging, and biobanking.

dGTEx Funding Partners:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)

For more information on dGTEx visit:
dGTEx.org
dGTEx Family Resource Page

Somatic Mosaicism Across Human Tissues (SMaHT) Network

Somatic Mosaicism Across Human Tissues (SMaHT) Network is an NIH Common Fund program that will provide the first comprehensive public resource for analyzing genetic variation due to somatic mosaicism in human tissues from all developmental layers in the human body. NDRI serves as the lead for the Tissue Procurement Center (TPC), in collaboration with the University of Maryland School of Medicine, Johns Hopkins All Children’s Hospital, and three partner OPOs. The TPC is responsible for collecting, storing, and distributing multiple tissues across body systems from a diverse pool of organ and tissue donors for the SMaHT network.

SMaHT Funding Partner:
Office of the Director (OD), Office of Strategic Coordination

For more information on SMaHT visit:
SMaHT.org
NIH SMaHT Resource

NDRI also partners with many corporate and non-profit partners. Some of our not-for-profit partners are below:

ALS Boston VA Brain Bank

To advance research on amyotrophic lateral sclerosis (ALS), often called Lou Gehrig’s disease, the Department of Veterans Affairs Biorepository Brain Bank (VABBB) collects, processes, stores and distributes ALS biospecimens for future scientific studies. NDRI helps VABBB obtain the samples they need to build the biorepository, or human tissue bank.

Bay Area Lyme Foundation

Lyme disease is a tick-borne infection caused by Borrelia burgdorferi bacteria. The Centers for Disease Control and Prevention (CDC) estimates that each year as many as 300,000 people in the United States are diagnosed with Lyme disease. NDRI is partnering with the Bay Area Lyme Foundation and its Lyme Disease Biobank to build a system for collecting and banking a diverse group of biospecimens for use by the Lyme disease research community.

Cystic Fibrosis Foundation

The Cystic Fibrosis (CF) Foundation is committed to finding a cure for CF. Since 2004, the CF Foundation has funded NDRI to provide a reliable source of human tissues from CF donors with different genotypes to facilitate research and drug development. NDRI has continuously met those needs by providing countless high-quality biospecimens, which the foundation can use in studies to further promote individualized treatment and specialized care for individuals affected by the disease.

National ALS Registry – Agency for Toxic Substances and Disease Registry (ATSDR)

NDRI has a special focus on Amyotrophic lateral sclerosis (ALS) through collaborations with the National ALS Biorepository. McKing Consulting Corporation contracted NDRI to participate in a study to explore methods for collecting and banking brain tissues from patients enrolled in the National ALS Registry, which is maintained by the federal Agency for Toxic Substances and Disease Registry (ATSDR). NDRI is supporting the ongoing maintenance of ATSDR database of ALS patients and is leading the collection of biospecimens from those donors to develop the biorepository to support ALS research.